Agentic payments and trustless commerce protocols cover the stack that lets autonomous agents and programmable wallets make, route and settle payments with minimized human intervention and cryptographic assurances. By 2026 this area focuses on composable standards (e.g., ERC-8183, x402, Etherlink) layered on existing account-abstraction work such as ERC-4337, paired with middleware connectors that let LLM-driven agents interact reliably with DeFi infrastructure. Practical implementations come from “MCP” server tooling that standardizes agent-to-protocol calls: Edwin (the Edwin DeFAI Layer) provides a TypeScript bridge for AI agents to interact with EVM, Solana and other chains; uniswap-trader-mcp automates multi-hop Uniswap swaps and price routing; token-revoke-mcp enumerates and revokes ERC‑20 allowances across 50+ EVM chains; Paradex MCP exposes perpetual futures trading; Solana Agent Kit and jupiter-mcp enable the same agentic flows on Solana; Kukapay and pool‑spy MCP servers supply aggregated on‑chain data and new‑pool feeds. Together these tools illustrate practical needs for standardized message formats, session-based approvals, gas abstraction, and revocation primitives. The combination of emerging protocol specs and multi-chain MCP tooling is timely because production use of autonomous agents is increasing, raising UX, security and compliance questions: how wallets grant scoped authority to agents, how approvals are revoked, how cross‑chain routing is optimized, and how off‑chain commerce commitments are settled trustlessly. For integrators and wallet builders this topic clarifies the interfaces and patterns—standards for commerce intent, agent session models, and MCP-based adapters—that enable safer, auditable agentic payments across DeFi ecosystems.