This topic covers tools and practices for detecting, triaging, and mitigating DeFi incidents in real time—with a focus on Solana‑specific incident frameworks such as STRIDE and SIRN—while addressing AI governance and post‑quantum transition needs. As DeFi continues to scale, fast on‑chain telemetry, structured threat modeling, and automated response playbooks are essential to contain exploits and limit systemic risk. The trend toward agentic AI in security operations changes how alerts are prioritized and actions are executed, while post‑quantum concerns are driving migration planning for cryptographic keys and signature schemes. Key classes of tools include AI orchestration and visibility platforms (e.g., Xilos) that provide enterprise‑grade monitoring of connected services and agent activity; virtual assistant and orchestration frameworks (IBM watsonx Assistant, StackAI) that enable no‑code or developer‑driven response playbooks and multi‑agent workflows; and developer AI assistants (GitHub Copilot, Tabnine, JetBrains AI Assistant) that accelerate creation and review of remediation code, smart contract fixes, and incident scripts. Together these tools support a pipeline from detection to containment: on‑chain anomaly detection and STRIDE/SIRN‑guided incident classification, AI‑assisted triage and runbook execution, and coordinated developer updates with governance controls. Practical considerations include enforcing AI security governance to limit unsafe autonomous actions, integrating post‑quantum migration plans into incident playbooks, and balancing automation with human oversight. The result is a pragmatic stack for teams that must respond to faster, higher‑impact DeFi incidents while preparing for cryptographic change and growing use of agentic AI in security operations.